Researchers identify brain mechanism behind depression

Researchers identify brain mechanism behind depression

415
SHARE

Today:- London, Dec – People suffer from major depressive disorders because of alterations in the activity and connectivity of brain systems underlying reward and memory, suggests new research.

The findings, published in the journal Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, provide clues as to which regions of the brain could be at the root of symptoms, such as reduced happiness and pleasure, or negative memories, in depression.

For the study, the researchers used a new approach to measure the influence of one brain region on another, referred to as effective connectivity, in depression.

The approach goes beyond the limitations of previous brain imaging studies, which show if — but not how — activity of different brain regions is related.

“The new method allows the effect of one brain region on another to be measured in depression, in order to discover more about which brain systems make causal contributions to depression,” said one of the researchers Edmund Rolls, Professor at University of Warwick in England.

The researchers compared 336 people with major depressive disorder to 350 healthy controls.

Brain regions involved in reward and subjective pleasure received less drive (or reduced effective connectivity) in patients, which may contribute to the decreased feeling of happiness in depression, the study showed.

In addition, brain regions involved in punishment and responses when a reward is not received had increased activity, providing evidence for the source of sadness that occurs in the disorder.

Memory-related areas of the brain had increased activity and connectivity in people with depression, which the authors suggest may be related to heightened memory processing, possibly of unpleasant memories, in depression.

“These findings are part of a concerted approach to better understand the brain mechanisms related to depression, and thereby to lead to new ways of understanding and treating depression,” Rolls said.
IANS

135 COMMENTS

  1. I think this is one of the most significant info for me. And i’m glad reading your article. But want to remark on some general things, The web site style is ideal, the articles is really nice : D. Good job, cheers|

  2. With havin so much content do you ever run into any issues of plagorism or copyright violation? My site has a lot of unique content I’ve either written myself or outsourced but it appears a lot of it is popping it up all over the web without my authorization. Do you know any solutions to help reduce content from being stolen? I’d definitely appreciate it.|

  3. It is perfect time to make some plans for the future and it’s time to be happy. I’ve read this post and if I could I wish to suggest you few interesting things or tips. Perhaps you could write next articles referring to this article. I desire to read even more things about it!|

  4. I love your blog.. very nice colors & theme. Did you design this website yourself or did you hire someone to do it for you? Plz respond as I’m looking to create my own blog and would like to find out where u got this from. kudos|

  5. Wow, fantastic blog layout! How long have you been blogging for? you make blogging look easy. The overall look of your web site is fantastic, let alone the content!|

  6. I know this if off topic but I’m looking into starting my own weblog and was curious what all is required to get set up? I’m assuming having a blog like yours would cost a pretty penny? I’m not very web smart so I’m not 100 certain. Any suggestions or advice would be greatly appreciated. Many thanks|

  7. Good day! This is my first visit to your blog! We are a team of volunteers and starting a new initiative in a community in the same niche. Your blog provided us beneficial information to work on. You have done a outstanding job!|

  8. What’s up every one, here every one is sharing such know-how, therefore it’s good to read this blog, and I used to go to see this blog all the time.|

  9. I’m impressed, I must say. Seldom do I come across a blog that’s both equally educative and interesting, and without a doubt, you have hit the nail on the head. The issue is an issue that not enough folks are speaking intelligently about. Now i’m very happy I came across this in my search for something concerning this.|

  10. Hey There. I found your blog using msn. This is a really well written article. I will be sure to bookmark it and return to read more of your useful information. Thanks for the post. I’ll definitely return.|

  11. I’ve been exploring for a bit for any high quality articles or weblog posts in this kind of house . Exploring in Yahoo I ultimately stumbled upon this web site. Reading this information So i’m satisfied to exhibit that I have a very just right uncanny feeling I came upon just what I needed. I so much for sure will make sure to do not forget this web site and give it a glance regularly.|

  12. I am really impressed with your writing skills and also with the layout on your blog. Is this a paid theme or did you modify it yourself? Anyway keep up the excellent quality writing, it’s rare to see a great blog like this one nowadays.|

  13. Thanks for the marvelous posting! I like your style. Very nice article, exactly what I needed. Thank you for putting this up. I simply must tell you that I love your blogs blog.

  14. Do you have a spam problem on this site; I also am a blogger, and I was wondering your situation; many of us have developed some nice procedures and we are looking to trade strategies with other folks, be sure to shoot me an e-mail if interested.|

  15. I’m not sure where you are getting your information, but good topic. I needs to spend some time learning much more or understanding more. Thanks for magnificent information I was looking for this info for my mission.|

  16. Terrific post but I was wanting to know if you could write a litte more on this topic? I’d be very grateful if you could elaborate a little bit more. Thank you!|

  17. Hey there just wanted to give you a quick heads up. The words in your post seem to be running off the screen in Internet explorer. I’m not sure if this is a formatting issue or something to do with web browser compatibility but I thought I’d post to let you know. The design look great though! Hope you get the issue solved soon. Kudos|

  18. Fascinating blog! Is your theme custom made or did you download it from somewhere? A theme like yours with a few simple adjustements would really make my blog jump out. Please let me know where you got your design. Cheers|

  19. you’re in point of fact a good webmaster. The web site loading speed is incredible. It kind of feels that you are doing any distinctive trick. Furthermore, The contents are masterpiece. you have done a great task in this topic!|

  20. I’m impressed, I have to admit. Rarely do I come across a blog that’s both educative and amusing, and without a doubt, you have hit the nail on the head. The problem is an issue that too few people are speaking intelligently about. I am very happy that I stumbled across this during my hunt for something relating to this.|

  21. May I simply just say what a relief to find someone who truly understands what they are talking about on the net. You certainly know how to bring a problem to light and make it important. More and more people ought to look at this and understand this side of your story. I was surprised that you’re not more popular given that you definitely possess the gift.|

  22. May I just say what a relief to find somebody who truly understands what they are talking about over the internet. You actually realize how to bring an issue to light and make it important. A lot more people ought to look at this and understand this side of your story. I can’t believe you are not more popular given that you surely possess the gift.|

  23. Hola! I’ve been reading your weblog for a long time now and finally got the bravery to go ahead and give you a shout out from Humble Tx! Just wanted to tell you keep up the fantastic work!|

  24. Do you have a spam issue on this blog; I also am a blogger, and I was wondering your situation; we have developed some nice procedures and we are looking to trade techniques with other folks, please shoot me an email if interested.|

  25. I’m really impressed along with your writing talents and also with the layout for your blog. Is that this a paid topic or did you customize it yourself? Either way stay up the excellent high quality writing, it is uncommon to peer a nice blog like this one these days..|

  26. Spot on with this write-up, I truly believe this website needs far more attention. I’ll probably be returning to see more, thanks for the info!|

  27. For most recent information you have to go to see world wide web and on world-wide-web I found this web page as a best website for latest updates.|

  28. I was very happy to discover this page. I need to to thank you for your time for this wonderful read!! I definitely loved every bit of it and i also have you saved as a favorite to look at new information on your web site.|

  29. Hi there would you mind letting me know which webhost you’re utilizing? I’ve loaded your blog in 3 different web browsers and I must say this blog loads a lot faster then most. Can you recommend a good hosting provider at a fair price? Many thanks, I appreciate it!|

  30. Someone essentially lend a hand to make severely posts I’d state. This is the very first time I frequented your website page and to this point? I amazed with the analysis you made to make this particular post incredible. Excellent job!|

  31. Hmm it appears like your blog ate my first comment (it was super long) so I guess I’ll just sum it up what I had written and say, I’m thoroughly enjoying your blog. I as well am an aspiring blog blogger but I’m still new to the whole thing. Do you have any tips and hints for first-time blog writers? I’d genuinely appreciate it.|

  32. It’s really a nice and useful piece of info. I am happy that you simply shared this helpful info with us. Please keep us up to date like this. Thank you for sharing.|

  33. Hello, Neat post. There is an issue along with your website in web explorer, would check this? IE nonetheless is the market chief and a good section of folks will omit your excellent writing due to this problem.|

  34. Hey there! This post couldn’t be written any better! Reading through this post reminds me of my good old room mate! He always kept chatting about this. I will forward this post to him. Pretty sure he will have a good read. Thank you for sharing!|

  35. I know this if off topic but I’m looking into starting my own blog and was wondering what all is required to get setup? I’m assuming having a blog like yours would cost a pretty penny? I’m not very web smart so I’m not 100 certain. Any recommendations or advice would be greatly appreciated. Thanks|

  36. Every weekend i used to visit this web site, for the reason that i wish for enjoyment, as this this web site conations genuinely pleasant funny stuff too.|

  37. Spot on with this write-up, I absolutely believe this web site needs a lot more attention. I’ll probably be returning to read through more, thanks for the information!|

  38. Do you have a spam issue on this blog; I also am a blogger, and I was wondering your situation; many of us have developed some nice methods and we are looking to trade solutions with other folks, be sure to shoot me an e-mail if interested.|

  39. I must thank you for the efforts you have put in writing this blog. I am hoping to view the same high-grade content from you later on as well. In fact, your creative writing abilities has encouraged me to get my own, personal website now ;)|

  40. Hey there! Do you use Twitter? I’d like to follow you if that would be okay. I’m undoubtedly enjoying your blog and look forward to new updates.|

  41. I’m not that much of a online reader to be honest but your blogs really nice, keep it up! I’ll go ahead and bookmark your website to come back down the road. Many thanks|

  42. I truly love your site.. Very nice colors & theme. Did you create this site yourself? Please reply back as I’m planning to create my very own website and would love to know where you got this from or exactly what the theme is named. Thank you!|

  43. Good post. I learn something new and challenging on blogs I stumbleupon everyday. It will always be useful to read content from other writers and practice a little something from other websites. |

  44. It’s really very difficult in this full of activity life to listen news on Television, therefore I just use world wide web for that reason, and take the newest news.|

  45. whoah this weblog is great i love reading your posts. Stay up the good work! You realize, lots of persons are searching around for this information, you could aid them greatly. |

  46. Hi there would you mind sharing which blog platform you’re working with? I’m planning to start my own blog soon but I’m having a hard time deciding between BlogEngine/Wordpress/B2evolution and Drupal. The reason I ask is because your layout seems different then most blogs and I’m looking for something unique. P.S Sorry for being off-topic but I had to ask!|

  47. What i do not understood is if truth be told how you’re no longer actually much more neatly-preferred than you may be right now. You are very intelligent. You realize thus considerably in terms of this subject, made me for my part believe it from so many varied angles. Its like men and women don’t seem to be involved until it is one thing to do with Lady gaga! Your personal stuffs excellent. All the time maintain it up!|

  48. What i don’t realize is if truth be told how you’re not actually much more neatly-liked than you might be now. You’re very intelligent. You know thus significantly in relation to this matter, made me individually believe it from so many various angles. Its like men and women are not interested unless it is one thing to do with Lady gaga! Your own stuffs great. At all times maintain it up!|

  49. Hey! I could have sworn I’ve been to this site before but after checking through some of the post I realized it’s new to me. Anyhow, I’m definitely happy I found it and I’ll be bookmarking and checking back frequently!|

  50. I think this is one of the most important info for me. And i am glad reading your article. But wanna remark on some general things, The site style is perfect, the articles is really great : D. Good job, cheers|

  51. Great post. I was checking constantly this weblog and I am impressed! Extremely useful info specially the final phase 🙂 I maintain such info much. I was seeking this particular info for a very lengthy time. Thanks and good luck. |

  52. hey there and thank you for your info – I have definitely picked up anything new from right here. I did however expertise several technical issues using this website, since I experienced to reload the site a lot of times previous to I could get it to load correctly. I had been wondering if your web host is OK? Not that I am complaining, but sluggish loading instances times will often affect your placement in google and could damage your high quality score if advertising and marketing with Adwords. Anyway I’m adding this RSS to my email and can look out for much more of your respective fascinating content. Make sure you update this again very soon.|

  53. Does your site have a contact page? I’m having trouble locating it but, I’d like to shoot you an email. I’ve got some suggestions for your blog you might be interested in hearing. Either way, great website and I look forward to seeing it expand over time.|

  54. Thanks , I’ve recently been looking for information about this topic for ages and yours is the greatest I have came upon till now. However, what about the conclusion? Are you positive in regards to the source?|

  55. Hmm is anyone else having problems with the pictures on this blog loading? I’m trying to figure out if its a problem on my end or if it’s the blog. Any feedback would be greatly appreciated.|

  56. Just want to say your article is as astounding. The clarity in your post is just excellent and that i can assume you’re knowledgeable in this subject. Well along with your permission allow me to clutch your RSS feed to stay updated with forthcoming post. Thank you 1,000,000 and please carry on the enjoyable work.|

  57. Oh my goodness! Impressive article dude! Thank you so much, However I am having difficulties with your RSS. I don’t understand the reason why I cannot subscribe to it. Is there anybody else getting identical RSS problems? Anybody who knows the answer will you kindly respond? Thanks!!|

  58. Hello! I realize this is somewhat off-topic however I needed to ask. Does building a well-established website like yours require a large amount of work? I’m completely new to running a blog however I do write in my diary every day. I’d like to start a blog so I can share my own experience and feelings online. Please let me know if you have any kind of suggestions or tips for new aspiring bloggers. Appreciate it!|

  59. Wow, incredible blog layout! How lengthy have you been blogging for? you made running a blog glance easy. The full glance of your site is great, let alone the content material!

  60. Have you ever thought about including a little bit more than just your articles? I mean, what you say is valuable and everything. But just imagine if you added some great graphics or videos to give your posts more, “pop”! Your content is excellent but with images and clips, this blog could undeniably be one of the greatest in its field. Terrific blog!|

  61. Hello There. I found your blog using msn. This is a really well written article. I’ll be sure to bookmark it and come back to read more of your useful info. Thanks for the post. I’ll certainly return.|

  62. Thanks for one’s marvelous posting! I really enjoyed reading it, you could be a great author.I will always bookmark your blog and definitely will come back very soon. I want to encourage you to definitely continue your great work, have a nice evening!|

  63. Great website. Lots of useful information here. I am sending it to a few friends ans additionally sharing in delicious. And naturally, thank you for your sweat!|

  64. Greetings from Ohio! I’m bored at work so I decided to check out your website on my iphone during lunch break. I enjoy the knowledge you provide here and can’t wait to take a look when I get home. I’m surprised at how fast your blog loaded on my phone .. I’m not even using WIFI, just 3G .. Anyhow, fantastic site!|

  65. My family members always say that I am killing my time here at web, however I know I am getting experience everyday by reading thes nice articles.|

  66. Howdy this is kind of of off topic but I was wondering if blogs use WYSIWYG editors or if you have to manually code with HTML. I’m starting a blog soon but have no coding know-how so I wanted to get guidance from someone with experience. Any help would be greatly appreciated!|

  67. I am no longer certain where you are getting your info, however good topic. I must spend some time learning much more or understanding more. Thank you for great info I was on the lookout for this info for my mission.|

  68. Great blog! Do you have any helpful hints for aspiring writers? I’m planning to start my own blog soon but I’m a little lost on everything. Would you recommend starting with a free platform like WordPress or go for a paid option? There are so many choices out there that I’m completely confused .. Any tips? Cheers!|

  69. I have been exploring for a little bit for any high-quality articles or weblog posts in this sort of area . Exploring in Yahoo I finally stumbled upon this web site. Studying this information So i’m glad to exhibit that I have a very just right uncanny feeling I discovered just what I needed. I so much definitely will make certain to do not fail to remember this web site and provides it a look regularly.|

  70. Hello there, simply turned into alert to your weblog through Google, and located that it’s really informative. I’m gonna be careful for brussels. I will be grateful for those who continue this in future. Numerous folks can be benefited from your writing. Cheers!|

  71. Aw, this was an incredibly nice post. Taking the time and actual effort to generate a good article… but what can I say… I put things off a lot and don’t manage to get nearly anything done.|

  72. It’s actually a nice and helpful piece of information. I’m glad that you just shared this useful information with us. Please keep us up to date like this. Thank you for sharing.|

  73. Hi! This post couldn’t be written any better! Reading through this post reminds me of my old room mate! He always kept talking about this. I will forward this write-up to him. Fairly certain he will have a good read. Many thanks for sharing!|

  74. Hi, i think that i saw you visited my site thus i came to “return the favor”.I’m trying to find things to enhance my web site!I suppose its ok to use a few of your ideas!!|

  75. Fantastic site. A lot of useful information here. I am sending it to several buddies ans additionally sharing in delicious. And of course, thank you for your effort!|

  76. We stumbled over here from a different website and thought I may as well check things out. I like what I see so i am just following you. Look forward to exploring your web page for a second time.|

  77. First off I would like to say wonderful blog! I had a quick question in which I’d like to ask if you don’t mind. I was interested to find out how you center yourself and clear your mind before writing. I have had a hard time clearing my thoughts in getting my ideas out there. I do take pleasure in writing but it just seems like the first 10 to 15 minutes are generally lost simply just trying to figure out how to begin. Any recommendations or tips? Thank you!|

  78. Attractive component to content. I just stumbled upon your blog and in accession capital to say that I acquire in fact loved account your weblog posts. Any way I’ll be subscribing to your feeds or even I fulfillment you get admission to constantly quickly.|

  79. You really make it seem so easy with your presentation but I find this topic to be really something which I think I would never understand. It seems too complicated and very broad for me. I’m looking forward for your next post, I will try to get the hang of it!|

  80. Thank you for the auspicious writeup. It in fact was a amusement account it. Look advanced to far added agreeable from you! By the way, how could we communicate?|

  81. Hmm it seems like your site ate my first comment (it was extremely long) so I guess I’ll just sum it up what I wrote and say, I’m thoroughly enjoying your blog. I too am an aspiring blog writer but I’m still new to everything. Do you have any tips and hints for beginner blog writers? I’d really appreciate it.|

  82. Wow, wonderful blog layout! How long have you been blogging for? you make blogging look easy. The overall look of your web site is great, as well as the content!|

  83. With havin so much written content do you ever run into any problems of plagorism or copyright infringement? My site has a lot of unique content I’ve either written myself or outsourced but it looks like a lot of it is popping it up all over the internet without my agreement. Do you know any ways to help stop content from being ripped off? I’d genuinely appreciate it.|

  84. Hello! I know this is kinda off topic nevertheless I’d figured I’d ask. Would you be interested in trading links or maybe guest writing a blog article or vice-versa? My site addresses a lot of the same topics as yours and I think we could greatly benefit from each other. If you might be interested feel free to send me an email. I look forward to hearing from you! Great blog by the way!|

  85. Good day! This is my first comment here so I just wanted to give a quick shout out and say I really enjoy reading through your blog posts. Can you suggest any other blogs/websites/forums that deal with the same topics? Thanks for your time!|

  86. Good day I am so thrilled I found your blog, I really found you by mistake, while I was searching on Yahoo for something else, Regardless I am here now and would just like to say thanks a lot for a fantastic post and a all round exciting blog (I also love the theme/design), I don’t have time to browse it all at the moment but I have bookmarked it and also included your RSS feeds, so when I have time I will be back to read a great deal more, Please do keep up the superb jo.|

  87. I got this web page from my pal who informed me about this web page and at the moment this time I am visiting this web site and reading very informative posts here.|

LEAVE A REPLY